Clinical Trials
Clinical trials at East Sydney Doctors
East Sydney Doctors has a long history of involvement in HIV and infectious disease research. Recently, the trials team has expanded their focus to include studies in respiratory, dermatology, and gynaecology. Our primary recruitment source is East Sydney Doctors's extensive database of loyal, long-standing patients. We take pride in our high rates of participant recruitment and retention.
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Our Areas of Research
HIV:
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Studies involving both HIV-naïve and experienced patients needing anti-HIV medications, including significant research such as START and EPIC Prep, which have yielded important findings in HIV prevention and treatment.
Hepatitis C:
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Research on Hepatitis C infection in people living with HIV.
Sexual Health:
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Treatment studies for gonorrhea and urinary tract infections (UTIs), including new antibiotic treatments for uncomplicated urogenital gonorrhea.
Respiratory Medicine:
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Prevention and treatment of respiratory illnesses.
Dermatology:
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Studies focusing on atopic dermatitis (eczema), rosacea, and plaque psoriasis.
Gynaecology:
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Research on women with high-grade cervical lesions (CIN2/CIN3).​
What Are Clinical Trials?
Clinical trials are medical research studies involving people. Before new medical treatments can be tested on voluntary participants, they must be thoroughly tested in the laboratory. Clinical trials examine the risks, causes, prevention, diagnosis, and treatment of various diseases and conditions. Some trials assess the side effects of existing medications, while others aim to introduce better treatments for the public.
At East Sydney Doctors, we conduct all phases of clinical trials, from phase 1 to phase 3.
Phase I Studies:
These are the initial studies involving people for a new drug. The primary goal of phase I studies is to determine the highest dose of the new treatment that can be administered safely without causing serious side effects. Although the treatment has been tested in laboratory and animal studies, the side effects in humans can’t always be predicted. These studies also help determine the best way to administer the new treatment.
Phase II Studies:
If a new treatment is found to be reasonably safe in phase I trials, it progresses to phase II trials to evaluate its effectiveness. The benefit or response that doctors look for depends on the treatment's goal. This could mean an improvement in the participant's health condition, the resolution of the health issue, or an enhanced quality of life.
Phase III Studies:
These trials compare the safety and effectiveness of the new treatment against the current standard treatment.
Our Facilities
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East Sydney Doctors has a dedicated area within the building for conducting clinical trials, with restricted access to all trial materials. This space includes temperature-controlled storage facilities, such as refrigerators and freezers. Experienced, ICH-GCP trained nurses are available on-site as needed, and there is an on-site pathology lab for blood collection and processing. Additionally, the close proximity to St Vincent’s Hospital provides an advantage for emergencies or referrals for specific tests that can only be performed in a hospital setting.
Our Clinical Trials Team
The clinical trials team at East Sydney Doctors is experienced, knowledgeable, and deeply passionate about patient care. They are dedicated to enhancing the patient journey throughout the trial process. Our team comprises experienced GPs, nurses, and clinical trial coordinators, all with a strong interest and many years of experience in conducting trials. We collaborate with a central private ethics committee, which allows for a fast turnaround of applications.
We are recruiting for these current trials....​​
Hidradenitis Suppurativa
Have you been diagnosed with hidradenitis suppurativa (HS)? The main goal of this study is to see if a new experimental treatment
improves symptoms associated with moderate to severe HS. If you qualify for the study, you will receive study-related treatment, tests,
and doctor visits at no cost to you!
Frequently Asked Questions
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What are the risks involved?
At East Sydney Doctors, our GPs primarily participate in the later stages of clinical trials after the investigational product has been extensively tested. During each trial visit, patients are assessed by the GP for any side effects or reactions to the study treatment. Patients can thoroughly read the consent form and receive all necessary information about the study drug. They have the opportunity to ask questions and discuss their treatment with their doctor and the trials team.
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Can I withdraw at any time during the study?
Participation in clinical trials is voluntary. Participants are free to withdraw at any time during the course of the study.
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How is my personal private information protected?
Clinical trials are conducted following Good Clinical Practice (GCP) guidelines. Participants' personal information remains de-identified and anonymous, ensuring their confidentiality throughout the study.
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Will I be compensated for my time?
There is no monetary reimbursement for participation in clinical trials; however volunteers can be reimbursed for their travel fees.
Would you like to be part of our clinical trials?
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If you're interested in participating in any of our current or upcoming clinical trials, please reach out to us for more details.
Email us:
trials@eastsydneydoctors.com.au
Call us:
02 9332 2531​